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FDA Information
Metaxalone is commercially available as a 400 mg tablet, under the brand name Skelaxin®. This product was approved by the FDA in 1962.
The first published reports about the use of metaxalone as a skeletal muscle relaxant appeared in the 1960s. Since then it has appeared in several reviews for this purpose, the most recent of which asserts that “metaxalone has the fewest reports of side effects and no reports of major safety issues” as compared with other skeletal muscle relaxants.
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